Mangosteen Pericarp

Mangosteen pericarp extract, derived from the rind of the tropical fruit Garcinia mangostana, is a rich source of bioactive polyphenols known as xanthones. This clinically inspired formulation is designed to support antioxidant protection, cellular health, and a balanced inflammatory response in adults and seniors.

Mangosteen Pericarp Extract - Advanced Antioxidant & Cellular Defense Support

Key Benefits

• Provides potent antioxidant protection against oxidative stress
• Supports a balanced inflammatory response
• Promotes cellular health and longevity
• Supports immune system function
• Helps protect connective tissue and joint integrity
• Supports healthy aging and metabolic resilience

Botanical Overview & Active Compounds

Mangosteen pericarp contains a unique class of polyphenolic compounds called xanthones, including alpha-mangostin, gamma-mangostin, and garcinone E. These compounds exhibit strong antioxidant activity and may influence cellular signaling pathways involved in oxidative stress, inflammation, and metabolic function.

The pericarp (outer rind) contains significantly higher concentrations of bioactive compounds compared to the fruit pulp, making it the preferred source for nutraceutical applications.

Mechanisms of Action

Antioxidant Defense

Xanthones demonstrate high free radical scavenging capacity and help reduce oxidative stress, which is associated with aging, cellular damage, and degenerative processes affecting multiple organ systems.

PubMed: Xanthones from mangosteen as potent antioxidant agents

Inflammatory Pathway Modulation

Mangosteen-derived xanthones may influence inflammatory signaling pathways, including NF-κB and COX-mediated processes, supporting a balanced inflammatory response relevant to joint and tissue health.

PubMed: Anti-inflammatory effects of mangosteen xanthones

Cellular Protection & Healthy Aging

By reducing oxidative stress and supporting mitochondrial function, mangosteen compounds may help protect cellular integrity and support healthy aging, particularly in populations experiencing increased oxidative burden.

Immune System Support

Polyphenols in mangosteen may support immune modulation and help maintain balanced immune responses, which are important for overall health and resilience.

Connective Tissue & Joint Support

Through antioxidant and inflammatory pathway support, mangosteen pericarp may help protect connective tissues, including cartilage and ligaments, from oxidative and inflammatory stressors.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.